A Comprehensive Review of Machine Learning’s Role within KOA

Authors

DOI:

https://doi.org/10.4108/eetiot.5329

Keywords:

Artificial Intelligence, Knee Osteoarthritis, Machine Learning, Deep Learning, TKR, classification, segmentation, object detection

Abstract

INTRODUCTION: Knee Osteoarthritis (KOA) is a degenerative joint disease, that predominantly affects the knee joint and causes significant global disability. The traditional methods prevailing in this field for proper diagnosis are very subjective and time-consuming, which hinders early detection. This study explored the integration of artificial intelligence (AI) in orthopedics, specifically the field of machine learning (ML) applications in KOA.

OBJECTIVES: The objective is to assess the effectiveness of Machine learning in KOA, besides focusing on disease progression, joint detection, segmentation, and its classification. ML algorithms are also applied to analyze the MRI and X-ray images for their proper classification and forecasting. The survey spanning from 2018 to 2022 investigated the treatment-seeking behavior of individuals with OA symptoms.

METHODS: Utilizing deep learning (CNN, RNN) and various ML algorithms (SVM, GBM), this study examined KOA. Machine learning was used as a subset of AI, and it played a pivotal role in healthcare, particularly in the field of medical imaging.  The analysis involved reviewing the studies from credible sources like Elsevier and Web of Science.

RESULTS: Current research in the field of medical imaging CAD revealed promising outcomes. Studies that utilized CNN demonstrated 80-90% accuracy on datasets like OAI and MOST, emphasizing its varied significance in vast clinical and imaging data archives.

CONCLUSION: This comprehensive analysis highlighted the evolving landscape of research in KOA. The role of machine learning in classification, segmentation, and diagnosis of severity is very much evident. The study also anticipates a future framework optimizing KOA detection and overall classification performance, with a strong emphasis on the potential for enhancement of knee osteoarthritis diagnostics.

Downloads

Download data is not yet available.
<br data-mce-bogus="1"> <br data-mce-bogus="1">

References

C. Kokkotis, S. Moustakidis, D. Tsaopoulos, V. Baltzopoulos, and G. Giakas, “Identifying robust risk factors for knee osteoarthritis progression: An evolutionary machine learning approach,” Healthc., vol. 9, no. 3, Mar. 2021, doi: 10.3390/healthcare9030260. DOI: https://doi.org/10.3390/healthcare9030260

P. Chen, L. Gao, X. Shi, K. Allen, and L. Yang, “Fully automatic knee osteoarthritis severity grading using deep neural networks with a novel ordinal loss,” Comput. Med. Imaging Graph., vol. 75, pp. 84–92, Jul. 2019, doi: 10.1016/j.compmedimag.2019.06.002. DOI: https://doi.org/10.1016/j.compmedimag.2019.06.002

K. Leung et al., “Prediction of total knee replacement and diagnosis of osteoarthritis by using deep learning on knee radiographs: Data from the osteoarthritis initiative,” Radiology, vol. 296, no. 3, pp. 584–593, Sep. 2020, doi: 10.1148/radiol.2020192091. DOI: https://doi.org/10.1148/radiol.2020192091

J. C. W. Cheung, A. Y. C. Tam, L. C. Chan, P. K. Chan, and C. Wen, “Superiority of multiple-joint space width over minimum-joint space width approach in the machine learning for radiographic severity and knee osteoarthritis progression,” Biology (Basel)., vol. 10, no. 11, 2021, doi: 10.3390/biology10111107. DOI: https://doi.org/10.3390/biology10111107

C. P. Pal, P. Singh, S. Chaturvedi, K. K. Pruthi, and A. Vij, “Epidemiology of knee osteoarthritis in India and related factors,” Indian J. Orthop., vol. 50, no. 5, pp. 518–522, 2016, doi: 10.4103/0019-5413.189608. DOI: https://doi.org/10.4103/0019-5413.189608

L. A. Rolim et al., “Enhanced Reader.pdf,” Nature, vol. 388. pp. 539–547, 2020.

S. A. El-Ghany, M. Elmogy, and A. A. A. El-Aziz, “A fully automatic fine tuned deep learning model for knee osteoarthritis detection and progression analysis,” Egypt. Informatics J., vol. 24, no. 2, pp. 229–240, Jul. 2023, doi: 10.1016/j.eij.2023.03.005. DOI: https://doi.org/10.1016/j.eij.2023.03.005

G. Kompella et al., “Segmentation of Femoral Cartilage from Knee Ultrasound Images Using Mask R-CNN,” in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, Institute of Electrical and Electronics Engineers Inc., Jul. 2019, pp. 966–969. doi: 10.1109/EMBC.2019.8857645. DOI: https://doi.org/10.1109/EMBC.2019.8857645

S. M. Ahmed and R. J. Mstafa, “A Comprehensive Survey on Bone Segmentation Techniques in Knee Osteoarthritis Research: From Conventional Methods to Deep Learning,” Diagnostics, vol. 12, no. 3. MDPI, Mar. 01, 2022. doi: 10.3390/diagnostics12030611. DOI: https://doi.org/10.3390/diagnostics12030611

H. A. Alshamrani, M. Rashid, S. S. Alshamrani, and A. H. D. Alshehri, “Osteo-NeT: An Automated System for Predicting Knee Osteoarthritis from X-ray Images Using Transfer-Learning-Based Neural Networks Approach,” Healthc., vol. 11, no. 9, 2023, doi: 10.3390/healthcare11091206. DOI: https://doi.org/10.3390/healthcare11091206

S. M. Ahmed and R. J. Mstafa, “Identifying Severity Grading of Knee Osteoarthritis from X-ray Images Using an Efficient Mixture of Deep Learning and Machine Learning Models,” Diagnostics, vol. 12, no. 12, Dec. 2022, doi: 10.3390/diagnostics12122939. DOI: https://doi.org/10.3390/diagnostics12122939

J. H. Cueva, D. Castillo, H. Espinós-Morató, D. Durán, P. Díaz, and V. Lakshminarayanan, “Detection and Classification of Knee Osteoarthritis,” Diagnostics, vol. 12, no. 10, Oct. 2022, doi: 10.3390/diagnostics12102362. DOI: https://doi.org/10.3390/diagnostics12102362

M. Ganesh Kumar and A. Das Goswami, “Automatic Classification of the Severity of Knee Osteoarthritis Using Enhanced Image Sharpening and CNN,” Appl. Sci., vol. 13, no. 3, Feb. 2023, doi: 10.3390/app13031658. DOI: https://doi.org/10.3390/app13031658

T. K. Yoo, D. W. Kim, S. B. Choi, E. Oh, and J. S. Park, “Simple scoring system and artificial neural network for knee osteoarthritis risk prediction: A cross-sectional study,” PLoS One, vol. 11, no. 2, pp. 1–17, 2016, doi: 10.1371/journal.pone.0148724. DOI: https://doi.org/10.1371/journal.pone.0148724

S. R. Hemanth, K. Tharun, C. R. H. S, S. Chadan, and M. Chadanmagar, “Cnn Based Automatic Detection of Knee Osteoarthritis Severity Using Mri Images and Image Processing Techniques,” Int. Res. J. Mod. Eng. Technol. Sci., no. 05, pp. 6461–6467, 2023, doi: 10.56726/irjmets40187. DOI: https://doi.org/10.56726/IRJMETS40187

M. Neubauer et al., “Artificial-Intelligence-Aided Radiographic Diagnostic of Knee Osteoarthritis Leads to a Higher Association of Clinical Findings with Diagnostic Ratings,” J. Clin. Med., vol. 12, no. 3, 2023, doi: 10.3390/jcm12030744. DOI: https://doi.org/10.3390/jcm12030744

H. Bonakdari, A. Jamshidi, J. P. Pelletier, F. Abram, G. Tardif, and J. Martel-Pelletier, “A warning machine learning algorithm for early knee osteoarthritis structural progressor patient screening,” Ther. Adv. Musculoskelet. Dis., vol. 13, pp. 1–16, 2021, doi: 10.1177/1759720X21993254. DOI: https://doi.org/10.1177/1759720X21993254

M. Binvignat et al., “Use of machine learning in osteoarthritis research: A systematic literature review,” RMD Open, vol. 8, no. 1, pp. 1–10, 2022, doi: 10.1136/rmdopen-2021-001998. DOI: https://doi.org/10.1136/rmdopen-2021-001998

L. S. Lee et al., “Artificial intelligence in diagnosis of knee osteoarthritis and prediction of arthroplasty outcomes: a review,” Arthroplasty, vol. 4, no. 1. BioMed Central Ltd, Dec. 01, 2022. doi: 10.1186/s42836-022-00118-7. DOI: https://doi.org/10.1186/s42836-022-00118-7

Z. Q. Zhao, P. Zheng, S. T. Xu, and X. Wu, “Object Detection with Deep Learning: A Review,” IEEE Trans. Neural Networks Learn. Syst., vol. 30, no. 11, pp. 3212–3232, 2019, doi: 10.1109/TNNLS.2018.2876865. DOI: https://doi.org/10.1109/TNNLS.2018.2876865

Y. Wang et al., “Causal Discovery in Radiographic Markers of Knee Osteoarthritis and Prediction for Knee Osteoarthritis Severity With Attention–Long Short-Term Memory,” Front. Public Heal., vol. 8, no. December, pp. 1–10, 2020, doi: 10.3389/fpubh.2020.604654. DOI: https://doi.org/10.3389/fpubh.2020.604654

R. T. Wahyuningrum, A. Lilik, and P. I, “11_ICAwST.2019.8923284.pdf,” 2019 IEEE 10th Int. Conf. Aware. Sci. Technol., pp. 1–6.

S. Kubkaddi and K. M. Ravikumar, “Early detection of knee osteoarthritis using SVM classifier,” J. Adv. Res. Dyn. Control Syst., vol. 10, no. 5 Special Issue, pp. 1524–1530, 2018.

C. Ntakolia, C. Kokkotis, S. Moustakidis, and D. Tsaopoulos, “A machine learning pipeline for predicting joint space narrowing in knee osteoarthritis patients,” in Proceedings - IEEE 20th International Conference on Bioinformatics and Bioengineering, BIBE 2020, Institute of Electrical and Electronics Engineers Inc., Oct. 2020, pp. 934–941. doi: 10.1109/BIBE50027.2020.00158. DOI: https://doi.org/10.1109/BIBE50027.2020.00158

R. T. Wahyuningrum, A. Yasid, and G. J. Verkerke, “Deep Neural Networks for Automatic Classification of Knee Osteoarthritis Severity Based on X-ray Images,” ACM Int. Conf. Proceeding Ser., vol. PartF16834, pp. 110–114, 2020, doi: 10.1145/3446999.3447020. DOI: https://doi.org/10.1145/3446999.3447020

Z. Wang, A. Chetouani, and R. Jennane, “A Confident Labelling Strategy Based on Deep Learning for Improving Early Detection of Knee OsteoArthritis,” Mar. 2023, [Online]. Available: http://arxiv.org/abs/2303.13203

A. Swiecicki et al., “Deep learning-based algorithm for assessment of knee osteoarthritis severity in radiographs matches performance of radiologists,” Comput. Biol. Med., vol. 133, 2021, doi: 10.1016/j.compbiomed.2021.104334. DOI: https://doi.org/10.1016/j.compbiomed.2021.104334

A. Jamshidi et al., “Identification of the most important features of knee osteoarthritis structural progressors using machine learning methods,” Ther. Adv. Musculoskelet. Dis., vol. 12, 2020, doi: 10.1177/1759720X20933468. DOI: https://doi.org/10.1177/1759720X20933468

M. Zakir Bellary, A. Professor, T. Habib Sardar, B. Aziz Musthafa, R. Sarkar, and A. Professor, “Medical Image Analysis of Knee Osteoarthritis using Modified Deep CNN,” J. Surv. Fish. Sci., vol. 10, no. 2S, pp. 133–144, 2023.

J. Antony, K. McGuinness, N. E. O’Connor, and K. Moran, “Quantifying radiographic knee osteoarthritis severity using deep convolutional neural networks,” Proc. - Int. Conf. Pattern Recognit., vol. 0, pp. 1195–1200, 2016, doi: 10.1109/ICPR.2016.7899799. DOI: https://doi.org/10.1109/ICPR.2016.7899799

A. Tiulpin and S. Saarakkala, “Automatic grading of individual knee osteoarthritis features in plain radiographs using deep convolutional neural networks,” Diagnostics, vol. 10, no. 11, Nov. 2020, doi: 10.3390/diagnostics10110932. DOI: https://doi.org/10.3390/diagnostics10110932

S. S. Gornale, P. U. Patravali, and R. R. Manza, “Detection of Osteoarthritis using Knee X-Ray Image Analyses: A Machine Vision based Approach,” Int. J. Comput. Appl., vol. 145, no. 1, pp. 975–8887, 2016. DOI: https://doi.org/10.5120/ijca2016910544

E. H. G. Oei et al., “The 15th international workshop on osteoarthritis imaging; ‘Open Up: The multifaceted nature of OA imaging,’” Osteoarthr. Imaging, vol. 2, no. 1, p. 100009, 2022, doi: 10.1016/j.ostima.2022.100009. DOI: https://doi.org/10.1016/j.ostima.2022.100009

A. Tiulpin, J. Thevenot, E. Rahtu, P. Lehenkari, and S. Saarakkala, “Automatic knee osteoarthritis diagnosis from plain radiographs: A deep learning-based approach,” Sci. Rep., vol. 8, no. 1, pp. 1–10, 2018, doi: 10.1038/s41598-018-20132-7. DOI: https://doi.org/10.1038/s41598-018-20132-7

C. Kokkotis, C. Ntakolia, S. Moustakidis, G. Giakas, and D. Tsaopoulos, “Explainable machine learning for knee osteoarthritis diagnosis based on a novel fuzzy feature selection methodology,” Phys. Eng. Sci. Med., vol. 45, no. 1, pp. 219–229, Mar. 2022, doi: 10.1007/s13246-022-01106-6. DOI: https://doi.org/10.1007/s13246-022-01106-6

M. Kotti, L. D. Duffell, A. A. Faisal, and A. H. McGregor, “Detecting knee osteoarthritis and its discriminating parameters using random forests,” Med. Eng. Phys., vol. 43, pp. 19–29, 2017, doi: 10.1016/j.medengphy.2017.02.004. DOI: https://doi.org/10.1016/j.medengphy.2017.02.004

Downloads

Published

07-03-2024

How to Cite

[1]
S. Rani, M. Memoria, T. Choudhury, and A. Sar, “A Comprehensive Review of Machine Learning’s Role within KOA”, EAI Endorsed Trans IoT, vol. 10, Mar. 2024.

Most read articles by the same author(s)