Modeling and Experimental Analysis of an In-body Area Nanonetwork

Abstract

Nanotechnology is gaining more and more consensus in several application fields, comprised in-body applications. Innovative therapies and diagnostic approaches are based on the use of injections or oral delivery of nanoparticles. The acceleration of this type of development makes very urgent a deeply and accurate analysis of the interaction between the nanoparticles and the biological fluid where the nanoparticles are immersed. In this paper, we focus on Titanium (Ti and its alloy (e.g.; TiO2) systems, given their specific features in terms of density, lack of cytotoxic effects, etc.. Specifically, we design and study an in-body system by characterizing the emission and diffusion processes. Further, we propose an experimental study of the morphology and other important characteristics (e.g. the pH of the particles, and the dielectric constant of the solution) of nano-TiO2 systems when immersed in a Ringer solution, in order to derive important information related to their potential toxicity inside the human body.